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According to a new study suggests that a common se

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Troubles With Heart Are Linked to HPV

by safdar javed on October 25, 2011

According to a new study suggests that a common sexually transmitted virus already linked to cancer may also cause cardiovascular disease.


Women infected with the human papillomavirus, or HPV, are two to three times as likely as uninfected women to have had a heart attack or stroke.


HPV is known to cause cancer of the cervix, vulva, penis, anus and throat, but the new study is the first to connect the virus to heart disease. The heart findings are not definitive: They show the virus may be associated with heart disease, but do not prove it caused the disease.

According to study HPV because the virus can sabotage a gene called p53, which normally protects the body from cancer and may also help prevent artery disease. Inactivation of p53 occurs in a variety of cancers, and the gene is considered to be a sort of guardian of the genome. Disabling p53 may also lead to inflammation and thickening in the walls of arteries.

The senior author of the study, Dr. Kenichi Fujise, a cardiologist said the research grew out of his quest to find out why some people have heart attacks even though they have none of the usual risk factors, like high cholesterol or high blood pressure. About 20 percent of patients with heart disease lack obvious risk factors, and researchers think those people must have other underlying problems that science has not yet figured out.

The infection persists and causes cancer in only a small minority. Two vaccines are approved to prevent HPV infection and are recommended
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